Moupriya Nag

Dr. Moupriya Nag

Assistant Professor, Department of Biotechnology
University of Engineering & Management (UEM), Kolkata

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Passionate about learning new scientific skills during the graduation, I was intrigued to spectroscopy and developed a keen interest in the field of single molecule spectroscopy. Using my practical knowledge of Physics, I was able to design a home-built Fluorescence Correlation Spectrometer during my doctorate. I loved the challenges and found it exciting to work on different aspects of Biophysical Chemistry and Photochemistry, such as, single molecule studies of protein unfolding/refolding, protein aggregation, protein-ligand interaction and in-vitro detection of metal ions.
My Postdoctoral work was focused on exploring the aggregation kinetics and mechanism of action of peptides associated with neurodegenerative diseases in presence of various membrane surfaces with solution NMR. It was a rewarding experience as I learnt various state of the art techniques used in a molecular biology Lab.
Currently, Working as an assistant professor at UEM Kolkata, I am in the process of establishing myself as a research scientist alongside of educating young students and inspiring research in basic science. My present research focusses on functional amyloids in bacteria and their relation in forming biofilms.

Work History



Research Interests

Doctoral Research:

Postdoctoral Research:

Research Skills



UV-Vis spectrophotometry, fluorimetry, Fluorescence Correlation Spectroscopy, circular dichroism, TEM, FT-IR, NMR (Basics only), TCSPC.

Protein Purification:

Septic and sterile techniques, optical microscopy, plating methods (streak, spread, pour, replica), techniques like gel filtration chromatography, ion-exchange chromatography, affinity chromatography. Handling of non-pathogenic cultures (E.Coli, BL21(DE3) strain), gel electrophoresis (SDS-PAGE).

Biological experiments:

Cell viability assay (LDH and MTT assay) on neuroblastoma cell line.


Statistical analysis using Origin, Adobe Photoshop, MS office, Maximum entropy method, NMR data analysis using TOPSPIN, SPARKY.

International Publications

  1. Sensing of hydrophobic cavity of serum albumin by an adenosine analogue: Fluorescence correlation and ensemble spectroscopic studies, Journal of Photochemistry and Photobiology B, 127 (2013) 202.
  2. Truncated or 2/2 hemoglobins: a new class of globins with novel structure and function, Journal of Proteins and Proteomics, 4 (2013) 45.
  3. Photophysical effects of nitric oxide and S- nitrosocysteine on acridine orange: use as sequential sensing platform for NO, cysteine, cysteine-NO and Hg+2 under physiological conditions, Analytical Methods, 6 (2013) 347.
  4. Development of a rhodamine-rhodanine based fluorescent mercury sensor and its use to monitor real time uptake and distribution of inorganic mercury in live zebrafish larvae, Analytical Chemistry, 86 (2014) 2740.
  5. Use of FCS to Study Protein Denaturation and Aggregation, Biophysical Journal, 106 (2014) 471a. (Conference Proceeding)
  6. A multicolor fluorescent peptide–nanoparticle scaffold: real time uptake and distribution in neuronal cells, New Journal of Chemistry, 38 (2014) 2709. (Cover article)
  7. Intermolecular disulfide bond formation promotes immunoglobulin aggregation: Investigation by fluorescence correlation spectroscopy, Proteins: Structure, Function, and Bioinformatics, 83 (2015) 169.
  8. Unusual denaturation trajectory of bovine gamma globulin studied by fluorescence correlation spectroscopy, Physical Chemistry Chemical Physics, 17 (2015) 19139.
  9. Comparative Study of the Antibiofilm Effect of plant extracts and antibiotic on Staphylococcus aureus ATCC 0352, International Journal of Basic and Applied Research, 8 (2018) 419.